Isotope Abundance Analysis
Convert your Agilent 5972/3/5 single quad data into elemental formulae and improve your confidence level in your NIST library identification.
The Tal-Aviv Isotope abundance analysis (IAA) software provides a novel method for significatly improved sample identification based on isotope abundance analysis (IAA). The software automatically converts the experimentally obtained isotope abundances into elemental formula information. More importantly, our IAA software, among other things, links with the NIST MS library and automatically confirms or rejects its identification. In case of a confirmation, the sample identification is unambiguous since the confirmation is done by an independent set of data and method. In the case of a rejection (such as when the compound is not included in the library or due to matrix interference), the IAA software independently provides a list of possible elemental formulas with declining order of matching to the experimental data, in similarity to costly accurate mass measurements. The Tal-Aviv IAA software can further help with sample identification through IAA of major high mass fragments, it provides unique information on the presence or lack-of certain elements and can help with isotope enrichment experiments.
A) The Tal-Aviv IAA software is automatically linked with the NIST library which is the industry standard identification method. Thus, the software significantly improves the identification confidence level using IAA information to uniquely confirm or reject the library identification results.
B) The combined Tal-Aviv IAA-NIST identification probability is much higher than that of accurate mass alternatives for compounds that are in the library database.
C) The combined Tal-Aviv IAA-NIST identification process results in sample molecule identification with its true chemical names and not just elemental formulas.
D) A major advantage of combined IAA and library search is that the library uniquely provides isomer identification from MS fragments while the IAA increases the probability of a correct elemental formula of that isomer. None of the available accurate mass methods and systems provide any isomer information.
E) The combined Tal-Aviv IAA-NIST identification uniquely eliminates false identification arising from missidentification of a frament ion as the molecular ion in the many cases in which the molecular ion is absent.
F) There is no need to use frequent or on-line mass tune with IAA.
G) IAA operates with standard centroid mode and does not require data collection in profile mode which generates x10 bigger files which are incompatible with NIST library search. Consequently the Tal-Aviv IAA software can also be used to analyze available old files.
H) The Tal-Aviv IAA software is very easy to use, either automated with NIST search (zero clicks) or via a one click of the mouse.
J) The Tal-Aviv IAA software is by far less expensive than any available accurate mass alternative.
For further information on IAA please read - Tal Alon and Aviv Amirav "Isotope Abundance Analysis Method and Software for Improved Sample Identification with the Supersonic GC-MS” Rapid Commun. Mass Spectrom. 20, 2579-2588 (2006). You may ask us for this paper and we shall Email it to you as a pdf file. Furthermore, we can Email you the Tal-Aviv IAA software manual upon your request for having closer information on the various software features.
We shall be happy to explore together the utilization and applicability of the Tal-Aviv IAA software of Aviv Analytical for your analysis and sample compounds. Please Email us your Chemstation mass chromatogram file and we shall Email you back our IAA analysis results. We trust that you will find the Tal-Aviv IAA software as easy to use and as the best tool for improving your sample identification. Thus, we are willing to give it for 30 days free trial following our communication and your purchase order so that if for any reason you do not like it you do not pay for it.
Below is the front screen of the Tal-Aviv IAA software.
